Ozempic, a medication first developed for Type 2 diabetes, has surged in popularity due to its weight-loss effects. By slowing digestion and extending feelings of fullness, it helps users cut back on food intake and lose weight quickly.
Like any drug, Ozempic comes with side effects. Common ones include nausea, constipation, and abdominal discomfort. However, some users are now reporting unexpected changes, sparking new discussions about its broader impact.

Beyond hair thinning, early aging, and smile changes, a newer concern has emerged online: what some are calling “Ozempic vulva.” Though not officially recognized, the term has gained traction as patients share experiences in online forums.
Dr. Tahery, a Los Angeles physician, notes three possible changes linked to the drug: sagging of the labia, weakened vaginal muscles, and dryness. These align with stories women are sharing about their bodies after rapid weight loss.
The explanation lies in how fat is lost. According to Dr. Justin Perron of the Australasian Society of Aesthetic Plastic Surgeons, significant weight loss affects fat throughout the body, not just the waist or face. This includes tissue in the mons pubis and labia, which may sag or lose volume.
Compounding this, Ozempic can also impact muscle mass. As pelvic muscles weaken, structural changes may occur, adding to concerns about vaginal health and strength.
Dr. Melanie Bone, a U.S. gynecologist, also points to hormonal shifts and reduced hydration as possible contributors to dryness and discomfort. These factors together may explain the intimate side effects some women report.
In response, some have turned to cosmetic treatments like dermal fillers for “genital rejuvenation.” While not all users will face these issues, the growing reports highlight the need for further research into Ozempic’s full impact beyond weight loss.